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Pharmacological analysis of the haemodynamic effects of 5-HT(1B/D) receptor agonists in the normotensive rat

1. The receptors involved in mediating the haemodynamic effects of three 5-HT(1B/D) receptor agonists were investigated in pentobarbitone anaesthetized rats (n=6–17 per group). 2. Cumulative intravenous (i.v.) infusions of rizatriptan and sumatriptan (from 0.63 to 2500 μg kg(−1); each dose over 5 mi...

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Detalhes bibliográficos
Main Authors: Pagniez, Fabrice, Valentin, Jean-Pierre, Vieu, Sylvie, Colpaert, Francis C, John, Gareth W
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565155/
https://ncbi.nlm.nih.gov/pubmed/9489607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701593
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