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Augmentation of human neutrophil and alveolar macrophage LTB(4) production by N-acetylcysteine: role of hydrogen peroxide

1. The actions of N-acetylcysteine (NAC) on hydrogen peroxide (H(2)O(2)) and leukotriene B(4) (LTB(4)) production by human resting and stimulated peripheral blood neutrophils and alveolar macrophages were investigated. 2. At a concentration of 100 μM, NAC significantly (P<0.01) suppressed the acc...

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Detalhes bibliográficos
Main Authors: Dent, Gordon, Rabe, Klaus F, Magnussen, Helgo
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564985/
https://ncbi.nlm.nih.gov/pubmed/9375974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701428
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