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Pharmacokinetic-pharmacodynamic modelling of the anti-lipolytic and anti-ketotic effects of the adenosine A(1)-receptor agonist N(6)-(p-sulphophenyl)adenosine in rats
1. The purpose of this study was to develop and validate an integrated pharmacokinetic-pharmacodynamic model for the anti-lipolytic effects of the adenosine A(1)-receptor agonist N(6)-(p-sulphophenyl)adenosine (SPA). Tissue selectivity of SPA was investigated by quantification of haemodynamic and an...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1997
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564970/ https://ncbi.nlm.nih.gov/pubmed/9351510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701412 |
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