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Effect of the molecular polymorphisms of human paraoxonase (PON1) on the rate of hydrolysis of paraoxon

1. The hydrolysis of organophosphate pesticides (OP) and nerve gases by serum paraoxonase (PON1) is an important factor determining their toxicity to mammals including man. The PON1 gene contains 2 polymorphic sites at amino acid positions 55 (L→M) and 192 (G→A, classically defined as the A and B ge...

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Detalhes bibliográficos
Main Authors: Mackness, Bharti, Mackness, Michael I, Arrol, Sharon, Turkie, Wajdi, Durrington, Paul N
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564940/
https://ncbi.nlm.nih.gov/pubmed/9313934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701390
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