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Effect of acute and chronic tramadol on [(3)H]-5-HT uptake in rat cortical synaptosomes

1. Tramadol hydrochloride is a centrally acting opioid analgesic, the efficacy and potency of which is only five to ten times lower than that of morphine. Opioid, as well as non-opioid mechanisms, may participate in the analgesic activity of tramadol. 2. [(3)H]-5-hydroxytryptamine (5-HT) uptake in r...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Giusti, Pietro, Buriani, Alessandro, Cima, Lorenzo, Lipartiti, Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564931/
https://ncbi.nlm.nih.gov/pubmed/9313939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701374
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