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Characterization of [(3)H]-prostaglandin E(2) binding to prostaglandin EP(4) receptors expressed with Semliki Forest virus
1. The human prostaglandin EP(4) receptor has been expressed by use of the Semliki Forest virus system. 2. In cell membranes [(3)H]-prostaglandin E(2) ([(3)H]-PGE(2)) bound to a high affinity site with a K(d) of 1.12±0.3 nM and a B(max) of 3.1±0.3 pmol mg(−1) protein. 3. In competition studies the r...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1997
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564884/ https://ncbi.nlm.nih.gov/pubmed/9283702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701332 |
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