Characterization of [(3)H]-prostaglandin E(2) binding to prostaglandin EP(4) receptors expressed with Semliki Forest virus

1. The human prostaglandin EP(4) receptor has been expressed by use of the Semliki Forest virus system. 2. In cell membranes [(3)H]-prostaglandin E(2) ([(3)H]-PGE(2)) bound to a high affinity site with a K(d) of 1.12±0.3 nM and a B(max) of 3.1±0.3 pmol mg(−1) protein. 3. In competition studies the r...

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Bibliografiska uppgifter
Huvudupphovsmän: Marshall, Fiona H, Patel, Kalpana, Lundstrom, Kenneth, Camacho, Janet, Foord, Steven M, Lee, Melanie G
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1997
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Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564884/
https://ncbi.nlm.nih.gov/pubmed/9283702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701332
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