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The selectivity and structural determinants of peptide antagonists at the CGRP receptor of rat, L6 myocytes
1. Potency orders were determined for a series of agonists and antagonists on the calcitonin gene-related peptide (CGRP) receptor of rat L6 myocytes. The agents tested were all shown to have been active against CGRP, amylin or adrenomedullin receptors. 2. AC187 had a pIC(50) of 6.8±0.10, making it 1...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1997
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564769/ https://ncbi.nlm.nih.gov/pubmed/9222559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701212 |
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