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The interaction of a new anti-tumour drug, KAR-2 with calmodulin
1. KAR-2 (3′′-(β-chloroethyl)-2′′,4′′-dioxo-3,5′′-spiro-oxazolidino-4-deacetoxy-vinblastine) is a semisynthetic bis-indol derivative, with high anti-microtubular and anti-tumour activities but with low toxicity. KAR-2, in contrast to other biologically active bis-indols (e.g. vinblastine), did not s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564757/ https://ncbi.nlm.nih.gov/pubmed/9222553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701190 |
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