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Inhibition by mibefradil, a novel calcium channel antagonist, of Ca(2+)- and volume-activated Cl(−) channels in macrovascular endothelial cells

1. We have studied the effects of mibefradil, a novel calcium antagonist, on the resting potential and ion channel activity of macrovascular endothelial cells (calf pulmonary artery endothelial cells, CPAE). The patch clamp technique was used to measure ionic currents and the Fura-II microfluorescen...

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Detalhes bibliográficos
Main Authors: Nilius, Bernd, Prenen, Jean, Kamouchi, Masahiro, Viana, Felix, Voets, Thomas, Droogmans, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564699/
https://ncbi.nlm.nih.gov/pubmed/9179399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701140
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