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Role of tachykinins in castor oil diarrhoea in rats

1. We set out to ascertain the role of tachykinins, neurokinin A and substance P, in castor oil-induced diarrhoea in rats as disclosed by the inhibitory effect of the non-peptide NK(1)- and NK(2)-receptor antagonists, SR 140333 and SR 48968, respectively. 2. SR 48968 (0.02 to 20 μg kg(−1), s.c. or p...

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Autors principals: Croci, Tiziano, Landi, Marco, Emonds-Alt, Xavier, Le Fur, Gérard, Maffrand, Jean-Pierre, Manara, Luciano
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564694/
https://ncbi.nlm.nih.gov/pubmed/9179376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701130
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