In vitro characterization of tachykinin NK(2)-receptors modulating motor responses of human colonic muscle strips

1. Human in vitro preparations of transverse or distal colonic circular smooth muscle were potently and dose-dependently contracted by neurokinin A (EC(50), 4.9 nM), the tachykinin NK(2)-receptor selective agonist [β-Ala(8)]neurokinin A (4–10) ([β-Ala(8)]NKA (4–10)) (EC(50), 5.0 nM), neurokinin B (E...

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Detalhes bibliográficos
Main Authors: Croci, Tiziano, Aureggi, Giulio, Manara, Luciano, Emonds-Alt, Xavier, Le Fur, Gerard, Maffrand, Jean-Pierre, Mukenge, Sylvain, Ferla, Gianfranco
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565515/
https://ncbi.nlm.nih.gov/pubmed/9720807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701960
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