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Absence of prostaglandin E(2)-induced hyperalgesia in NMDA receptor ε subunit knockout mice

1. We have previously found that intrathecal administration of prostaglandins E(2) (PGE(2)) and D(2) (PGD(2)) into conscious mice induced hyperalgesia by the hot plate test. The present study investigated the involvement of N-methyl-D-aspartate (NMDA) receptor in the prostaglandin-induced hyperalges...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Minami, Toshiaki, Sugatani, Junko, Sakimura, Kenji, Abe, Manabu, Mishina, Masayoshi, Ito, Seiji
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564625/
https://ncbi.nlm.nih.gov/pubmed/9113374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701067
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