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Absence of prostaglandin E(2)-induced hyperalgesia in NMDA receptor ε subunit knockout mice

1. We have previously found that intrathecal administration of prostaglandins E(2) (PGE(2)) and D(2) (PGD(2)) into conscious mice induced hyperalgesia by the hot plate test. The present study investigated the involvement of N-methyl-D-aspartate (NMDA) receptor in the prostaglandin-induced hyperalges...

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Detalhes bibliográficos
Main Authors: Minami, Toshiaki, Sugatani, Junko, Sakimura, Kenji, Abe, Manabu, Mishina, Masayoshi, Ito, Seiji
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564625/
https://ncbi.nlm.nih.gov/pubmed/9113374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701067
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