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Enhancement of the response to purinergic agonists in P2Y(1) transfected 1321N1 cells by antagonists suramin and PPADS

1. We have previously shown that both suramin and pyridoxal-phosphate-6-azophenyl-2′, 4′ disulphonic acid (PPADS) act as antagonists at transfected P2Y(1) receptors. Here we show that under certain experimental conditions these two P2 antagonists can enhance the response to agonists acting at these...

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Bibliographic Details
Main Authors: Brown, Colin A, Charlton, Steven J, Boarder, Michael R
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564572/
https://ncbi.nlm.nih.gov/pubmed/9134216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701010
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