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Inhibition of [(3)H]-U69593 binding and the cardiac effects of U50,488H by calcium channel blockers in the rat heart

1. The calcium channel blockers (CCBs), nifedipine, nicardipine, diltiazem and verapamil, were used to displace the binding of [(3)H]-U69593 ((5a,7a,8b)-(+)-N-methyl-N-(7-[1-pyrrolidinyl]-1-oxaspiro[4,5]dec-8-yl)-benzeneacetamide), a specific κ-opioid agonist, in the rat cardiac sarcolemma. The CCBs...

詳細記述

保存先:
書誌詳細
主要な著者: Zhang, Wei-Min, Wang, Hong-Xin, Xia, Qiang, Wong, Tak-Ming
フォーマット: Artigo
言語:Inglês
出版事項: 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564545/
https://ncbi.nlm.nih.gov/pubmed/9138688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700985
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