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Characteristics of L-type calcium channel blockade by lacidipine in guinea-pig ventricular myocytes
1. The Ca(2+)-antagonistic properties of lacidipine were investigated in patch-clamp guinea-pig ventricular myocytes. 2. In basal conditions, 0.1 μM lacidipine reduced the action potential duration, associated with a decrease in the L-type calcium current (I(Ca,L)) to 66±4% of the control value, wit...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1997
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564510/ https://ncbi.nlm.nih.gov/pubmed/9051306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700951 |
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