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Characteristics of L-type calcium channel blockade by lacidipine in guinea-pig ventricular myocytes

1. The Ca(2+)-antagonistic properties of lacidipine were investigated in patch-clamp guinea-pig ventricular myocytes. 2. In basal conditions, 0.1 μM lacidipine reduced the action potential duration, associated with a decrease in the L-type calcium current (I(Ca,L)) to 66±4% of the control value, wit...

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Detaylı Bibliyografya
Asıl Yazarlar: Cerbai, Elisabetta, Giotti, Alberto, Mugelli, Alessandro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564510/
https://ncbi.nlm.nih.gov/pubmed/9051306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700951
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