The effect of the protein phosphatases inhibitor cantharidin on β-adrenoceptor-mediated vasorelaxation

1. Cantharidin, an inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A), increased basal tone of bovine isolated coronary artery rings (CARs) with and without endothelium in a time- and concentration-dependent manner with pEC(50) values of about 5.1 and 5.2, respectively, for both preparatio...

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Autori principali: Knapp, Jörg, Bokník, Peter, Linck, Bettina, Lüss, Hartmut, Müller, Frank U, Nacke, Peter, Neumann, Joachim, Vahlensieck, Ute, Schmitz, Wilhelm
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564485/
https://ncbi.nlm.nih.gov/pubmed/9031745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700929
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