Negative chronotropic and inotropic effects exerted by diadenosine hexaphosphate (AP6A) via A1-adenosine receptors.

1. Diadenosine hexaphosphate (AP6A) exerts vasoconstrictive effects. The purpose of this study was to investigate whether AP6A has any effect on cardiac function. 2. The effects of AP6A (0.1-100 microM) on cardiac contractility and frequency were studied in guinea-pig and human isolated cardiac prep...

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Detalhes bibliográficos
Main Authors: Vahlensieck, U., Bokník, P., Knapp, J., Linck, B., Müller, F. U., Neumann, J., Herzig, S., Schlüter, H., Zidek, W., Deng, M. C., Scheld, H. H., Schmitz, W.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1915918/
https://ncbi.nlm.nih.gov/pubmed/8922729
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