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The inhibitory effects of mercaptoalkylguanidines on cyclo-oxygenase activity

1. It has been proposed that in inflammatory conditions, in which both the inducible isoforms of nitric oxide synthase (iNOS) and cyclo-oxygenase (COX-2) are induced, inhibition of NOS also results in inhibition of arachidonic acid metabolism. In the present study we have investigated whether mercap...

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Detalhes bibliográficos
Main Authors: Zingarelli, Basilia, Southan, Garry J, Gilad, Elijah, O'Connor, Michael, Salzman, Andrew L, Szabó, Csaba
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564467/
https://ncbi.nlm.nih.gov/pubmed/9031736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700892
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