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Inhibition by the immunosuppressive agent FK-506 of antigen-induced airways eosinophilia and bronchial hyperreactivity in mice

1. The effect of the immunosuppressive agent, FK-506, on allergen-induced airways eosinophilia and bronchial hyperreactivity (BHR) in hyper IgE mice (BP2 selection) was investigated. 2. Administration of FK-506 at 2 mg kg(−1) s.c., 1 h before and 5 h after the first of four ovalbumin challenges, red...

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Detalhes bibliográficos
Main Authors: Eum, Seok-Yong, Zuany-Amorium, Claudia, Lefort, Jean, Pretolani, Marina, Vargaftig, B Boris
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564338/
https://ncbi.nlm.nih.gov/pubmed/9117088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700860
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