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Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling
Recent studies of yeast G1 DNA damage response have identified characteristic changes in chromatin adjacent to double-strand breaks (DSBs). Histone H2A (yeast H2AX) is rapidly phosphorylated on S129 by the kinase Tel1 (ATM) over a domain extending kilobases from the DSB. The adaptor protein Rad9 (53...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564209/ https://ncbi.nlm.nih.gov/pubmed/16940359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511192103 |
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