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Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling

Recent studies of yeast G1 DNA damage response have identified characteristic changes in chromatin adjacent to double-strand breaks (DSBs). Histone H2A (yeast H2AX) is rapidly phosphorylated on S129 by the kinase Tel1 (ATM) over a domain extending kilobases from the DSB. The adaptor protein Rad9 (53...

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Main Authors: Javaheri, Ali, Wysocki, Robert, Jobin-Robitaille, Olivier, Altaf, Mohammed, Côté, Jacques, Kron, Stephen J.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564209/
https://ncbi.nlm.nih.gov/pubmed/16940359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511192103
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