Critical Role of 15-Lipoxygenase-1 in Colorectal Epithelial Cell Terminal Differentiation and Tumorigenesis

Terminal differentiation is an important event for maintaining normal homeostasis in the colorectal epithelium, and the loss of apoptosis is an important mechanism underlying colorectal tumorigenesis. The very limited current data on the role of lipoxygenase (LOX) metabolism in tumorigenesis suggest...

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Autors principals: Shureiqi, Imad, Wu, Yuanqing, Chen, Dongning, Yang, Xiu L., Guan, Baoxiang, Morris, Jeffrey S., Yang, Peiying, Newman, Robert A., Broaddus, Russell, Hamilton, Stanley R., Lynch, Patrick, Levin, Bernard, Fischer, Susan M., Lippman, Scott M.
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564070/
https://ncbi.nlm.nih.gov/pubmed/16357157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-2180
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