AICAR inhibits adipocyte differentiation in 3T3L1 and restores metabolic alterations in diet-induced obesity mice model

BACKGROUND: Obesity is one of the principal causative factors involved in the development of metabolic syndrome. AMP-activated protein kinase (AMPK) is an energy sensor that regulates cellular metabolism. The role of AMP-activated protein kinase in adipocyte differentiation is not completely underst...

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Main Authors: Giri, Shailendra, Rattan, Ramandeep, Haq, Ehtishamul, Khan, Mushfiquddin, Yasmin, Rifat, Won, Je-song, Key, Lyndon, Singh, Avtar K, Singh, Inderjit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564022/
https://ncbi.nlm.nih.gov/pubmed/16901342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-7075-3-31
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