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Adeno-Associated Virus Type 2 Contains an Integrin α5β1 Binding Domain Essential for Viral Cell Entry

Integrins have been implicated as coreceptors in the infectious pathways of several nonenveloped viruses. For example, adenoviruses are known to interact with αV integrins by virtue of a high-affinity arginine-glycine-aspartate (RGD) domain present in the penton bases of the capsids. In the case of...

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Bibliografski detalji
Glavni autori: Asokan, Aravind, Hamra, Julie B., Govindasamy, Lakshmanan, Agbandje-McKenna, Mavis, Samulski, Richard J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563945/
https://ncbi.nlm.nih.gov/pubmed/16940508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00843-06
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