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Inhibition by Woodchuck Hepatitis Virus of Class I Major Histocompatibility Complex Presentation on Hepatocytes Is Mediated by Virus Envelope Pre-S2 Protein and Can Be Reversed by Treatment with Gamma Interferon

Presentation of class I major histocompatibility complex (MHC) is severely down-regulated on hepatocytes in chronic hepatitis caused by woodchuck hepatitis virus (WHV). To determine which of the viral proteins mediates class I MHC antigen suppression, cultured normal woodchuck hepatocytes were trans...

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Bibliographic Details
Main Authors: Wang, Jinguo, Michalak, Tomasz I.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563886/
https://ncbi.nlm.nih.gov/pubmed/16912304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00830-06
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