Role of the Envelope Genetic Context in the Development of Enfuvirtide Resistance in Human Immunodeficiency Virus Type 1-Infected Patients

Acquired human immunodeficiency virus type 1(HIV-1) resistance to the fusion inhibitor enfuvirtide (ENF) is primarily associated with mutations within the highly conserved first heptad repeat (HR1) region of gp41. Viral env sequences, however, are remarkably variable, and the envelope genetic backgr...

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Main Authors: Labrosse, Béatrice, Morand-Joubert, Laurence, Goubard, Armelle, Rochas, Séverine, Labernardière, Jean-Louis, Pacanowski, Jerôme, Meynard, Jean-Luc, Hance, Allan J., Clavel, François, Mammano, Fabrizio
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2006
主題:
Vaccines and Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563884/
https://ncbi.nlm.nih.gov/pubmed/16912327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02706-05
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