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The NS5A Protein of Bovine Viral Diarrhea Virus Contains an Essential Zinc-Binding Site Similar to That of the Hepatitis C Virus NS5A Protein

The recent demonstration that the NS5A protein of hepatitis C virus (HCV) contains an unconventional zinc-binding site with the format Cx(17)CxCx(20)C and the presence of a similar sequence element in the NS5A proteins of members of the Pestivirus genus has led to the hypothesis that the NS5A protei...

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Detalhes bibliográficos
Main Authors: Tellinghuisen, Timothy L., Paulson, Matthew S., Rice, Charles M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563740/
https://ncbi.nlm.nih.gov/pubmed/16840325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00358-06
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