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Autoactivation of the Epstein-Barr Virus Oncogenic Protein LMP1 during Type II Latency through Opposite Roles of the NF-κB and JNK Signaling Pathways

Epstein-Barr virus (EBV) is associated with several human malignancies where it expresses limited subsets of latent proteins. Of the latent proteins, latent membrane protein 1 (LMP1) is a potent transforming protein that constitutively induces multiple cell signaling pathways and contributes to EBV-...

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Main Authors: Goormachtigh, Gautier, Ouk, Tan-Sothéa, Mougel, Alexandra, Tranchand-Bunel, Denis, Masy, Eric, Le Clorennec, Christophe, Feuillard, Jean, Bornkamm, Georg W., Auriault, Claude, Manet, Evelyne, Fafeur, Véronique, Adriaenssens, Eric, Coll, Jean
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563735/
https://ncbi.nlm.nih.gov/pubmed/16840319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02052-05
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