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Amyloid-β peptide levels in brain are inversely correlated with insulysin activity levels in vivo

Factors that elevate amyloid-β (Aβ) peptide levels are associated with an increased risk for Alzheimer's disease. Insulysin has been identified as one of several proteases potentially involved in Aβ degradation based on its hydrolysis of Aβ peptides in vitro. In this study, in vivo levels of br...

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Autori principali: Miller, Bonnie C., Eckman, Elizabeth A., Sambamurti, Kumar, Dobbs, Nicole, Chow, K. Martin, Eckman, Christopher B., Hersh, Louis B., Thiele, Dwain L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC156353/
https://ncbi.nlm.nih.gov/pubmed/12732730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1031520100
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