Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats

Tauroursodeoxycholic acid (TUDCA), an endogenous bile acid, modulates cell death by interrupting classic pathways of apoptosis. Intracerebral hemorrhage (ICH) is a devastating acute neurological disorder, without effective treatment, in which a significant loss of neuronal cells is thought to occur...

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Bibliografiske detaljer
Main Authors: Rodrigues, Cecilia M. P., Solá, Susana, Nan, Zhenhong, Castro, Rui E., Ribeiro, Paulo S., Low, Walter C., Steer, Clifford J.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC156330/
https://ncbi.nlm.nih.gov/pubmed/12721362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1031632100
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