Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats

Tauroursodeoxycholic acid (TUDCA), an endogenous bile acid, modulates cell death by interrupting classic pathways of apoptosis. Intracerebral hemorrhage (ICH) is a devastating acute neurological disorder, without effective treatment, in which a significant loss of neuronal cells is thought to occur...

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Detalhes bibliográficos
Main Authors: Rodrigues, Cecilia M. P., Solá, Susana, Nan, Zhenhong, Castro, Rui E., Ribeiro, Paulo S., Low, Walter C., Steer, Clifford J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156330/
https://ncbi.nlm.nih.gov/pubmed/12721362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1031632100
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