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Activation of CD4 T cells by Raf-independent effectors of Ras

Small GTPase Ras is capable of mediating activation in T lymphocytes by using Raf kinase-dependent signaling pathway. Other effectors of Ras exist, however, suggesting that targets of Ras alternative to Raf may also contribute to T cell functions. Here we demonstrate that Ras(V12G37) mutant that fai...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Czyzyk, Jan, Brogdon, Jennifer L., Badou, Abdallah, Henegariu, Octavian, Preston Hurlburt, Paula, Flavell, Richard, Bottomly, Kim
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156316/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12721365/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1031494100
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