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Hippocalcin Functions as a Calcium Sensor in Hippocampal LTD
It is not fully understood how NMDAR-dependent LTD causes Ca(2+)-dependent endocytosis of AMPARs. Here we show that the neuronal Ca(2+)sensor hippocalcin binds the β2-adaptin subunit of the AP2 adaptor complex and that along with GluR2 these coimmunoprecipitate in a Ca(2+)-sensitive manner. Infusion...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1563146/ https://ncbi.nlm.nih.gov/pubmed/16102532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2005.06.014 |
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