Hippocalcin Functions as a Calcium Sensor in Hippocampal LTD

It is not fully understood how NMDAR-dependent LTD causes Ca(2+)-dependent endocytosis of AMPARs. Here we show that the neuronal Ca(2+)sensor hippocalcin binds the β2-adaptin subunit of the AP2 adaptor complex and that along with GluR2 these coimmunoprecipitate in a Ca(2+)-sensitive manner. Infusion...

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Hlavní autoři: Palmer, Claire L., Lim, Wonil, Hastie, Peter G.R., Toward, Marie, Korolchuk, Viktor I., Burbidge, Stephen A., Banting, George, Collingridge, Graham L., Isaac, John. T.R., Henley, Jeremy M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563146/
https://ncbi.nlm.nih.gov/pubmed/16102532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2005.06.014
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