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Caspase-mediated processing of the Drosophila NF-κB factor Relish

The NF-κB-like transcription factor Relish plays a central role in the innate immune response of Drosophila. Unlike other NF-κB proteins, Relish is activated by endoproteolytic cleavage to generate a DNA-binding Rel homology domain and a stable IκB-like fragment. This signal-induced endoproteolysis...

Ausführliche Beschreibung

Gespeichert in:
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Stöven, Svenja, Silverman, Neal, Junell, Anna, Hedengren-Olcott, Marika, Erturk, Deniz, Engström, Ylva, Maniatis, Tom, Hultmark, Dan
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Biological Sciences
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156314/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12732719/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1035902100
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