Anthrax lethal factor represses glucocorticoid and progesterone receptor activity

We report here that a bacterial toxin, anthrax lethal toxin (LeTx), at very low concentrations represses glucocorticoid receptor (GR) transactivation in a transient transfection system and the activity of an endogenous GR-regulated gene in both a cellular system and an animal model. This repression...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Webster, Jeanette I., Tonelli, Leonardo H., Moayeri, Mahtab, Simons, S. Stoney, Leppla, Stephen H., Sternberg, Esther M.
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 2003
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156265/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12724519/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1036973100
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