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Expanding tRNA recognition of a tRNA synthetase by a single amino acid change

Aspartyl-tRNA synthetase (AspRS) occurs in two types: the discriminating enzyme (D-AspRS) forms only Asp-tRNA(Asp), whereas the nondiscriminating enzyme (ND-AspRS) also synthesizes Asp-tRNA(Asn), which is a required intermediate for protein synthesis in many organisms. We attempted to expand the tRN...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Feng, Liang, Tumbula-Hansen, Debra, Toogood, Helen, Söll, Dieter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156260/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12730374/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0631525100
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