A Domain in the C-Terminal Region of Latency-Associated Nuclear Antigen 1 of Kaposi's Sarcoma-Associated Herpesvirus Affects Transcriptional Activation and Binding to Nuclear Heterochromatin

The latency-associated nuclear antigen 1 (LANA-1) of Kaposi's sarcoma-associated herpesvirus (KSHV) is required for the maintenance and replication of viral episomal DNA. The binding sites for nuclear heterochromatin and transcriptional repressor complexes are located in an amino-terminal regio...

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Autores principales: Viejo-Borbolla, Abel, Kati, Emrah, Sheldon, Julie A., Nathan, Kavita, Mattsson, Karin, Szekely, Laszlo, Schulz, Thomas F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC156177/
https://ncbi.nlm.nih.gov/pubmed/12768028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.12.7093-7100.2003
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