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The PDZ Ligand Domain of the Human Papillomavirus Type 16 E6 Protein Is Required for E6's Induction of Epithelial Hyperplasia In Vivo

Human papillomaviruses (HPVs) are the causative agent of warts. Infections with high-risk HPVs are associated with anogenital and head and neck cancers. One of the viral genes responsible for HPV's oncogenic activity is E6. Mice expressing the HPV-16 E6 protein in their epidermis (K14E6(WT)) develop...

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Publicado en:J Virol
Autores principales: Nguyen, Marie L., Nguyen, Minh M., Lee, Denis, Griep, Anne E., Lambert, Paul F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2003
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156174/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12768014/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.12.6957-6964.2003
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