Replicating Parvoviruses That Target Colon Cancer Cells

The wnt signaling pathway is constitutively activated in colon tumors by mutations in the adenomatous polyposis coli and β-catenin genes. We have modified the minute virus of mice (MVM) P4 promoter to make it responsive to wnt signaling by inserting binding sites for the heterodimeric β-catenin/Tcf...

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Bibliografiska uppgifter

I publikationen:	J Virol
Huvudupphov:	Malerba, M., Daeffler, L., Rommelaere, J., Iggo, R. D.
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology (ASM) 2003
Ämnen:	Gene Therapy
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156172/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12767988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.12.6683-6691.2003
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