Determinants of Increased Replicative Capacity of Serially Passaged Simian Immunodeficiency Virus with nef Deleted in Rhesus Monkeys

Most rhesus macaques infected with simian immunodeficiency virus SIVmac239 with nef deleted (either Δnef or ΔnefΔvprΔUS [Δ3]) control viral replication and do not progress to AIDS. Some monkeys, however, develop moderate viral load set points and progress to AIDS. When simian immunodeficiency viruse...

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Detalhes bibliográficos
Main Authors: Alexander, Louis, Illyinskii, Petr O., Lang, Sabine M., Means, Robert E., Lifson, Jeffrey, Mansfield, Keith, Desrosiers, Ronald C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156171/
https://ncbi.nlm.nih.gov/pubmed/12768002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.12.6823-6835.2003
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