Structure-Function Analysis of Herpes Simplex Virus Type 1 gD and gH-gL: Clues from gDgH Chimeras

In alphaherpesviruses, glycoprotein B (gB), gD, gH, and gL are essential for virus entry. A replication-competent gL-null pseudorabies virus (PrV) (B. G. Klupp and T. C. Mettenleiter, J. Virol. 73:3014-3022, 1999) was shown to express a gDgH hybrid protein that could replace gD, gH, and gL in cell-c...

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Detalhes bibliográficos
Main Authors: Cairns, Tina M., Milne, Richard S. B., Ponce-de-Leon, Manuel, Tobin, Deanna K., Cohen, Gary H., Eisenberg, Roselyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156167/
https://ncbi.nlm.nih.gov/pubmed/12767993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.12.6731-6742.2003
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