Functional fluorescent protein insertions in herpes simplex virus gB report on gB conformation before and after execution of membrane fusion.
Entry of herpes simplex virus (HSV) into a target cell requires complex interactions and conformational changes by viral glycoproteins gD, gH/gL, and gB. During viral entry, gB transitions from a prefusion to a postfusion conformation, driving fusion of the viral envelope with the host cell membrane...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2014-09-01
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| Serier: | PLoS Pathogens |
| Online adgang: | http://europepmc.org/articles/PMC4169481?pdf=render |
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