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Basic Residues of the Helix Six Domain of Influenza Virus M1 Involved in Nuclear Translocation of M1 Can Be Replaced by PTAP and YPDL Late Assembly Domain Motifs

Influenza type A virus matrix (M1) protein possesses multiple functional motifs in the helix 6 (H6) domain (amino acids 91 to 105), including nuclear localization signal (NLS) (101-RKLKR-105) involved in translocating M1 from the cytoplasm into the nucleus. To determine the role of the NLS motif in...

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Detalhes bibliográficos
Main Authors: Hui, Eric Ka-Wai, Barman, Subrata, Yang, Tae Yong, Nayak, Debi P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156155/
https://ncbi.nlm.nih.gov/pubmed/12768027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.12.7078-7092.2003
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