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Effects of Rho Kinase and Actin Stress Fibers on Sustained Extracellular Signal-Regulated Kinase Activity and Activation of G(1) Phase Cyclin-Dependent Kinases

We recently reported that Rho kinase is required for sustained ERK signaling and the consequent mid-G(1) phase induction of cyclin D1 in fibroblasts. The results presented here indicate that these Rho kinase effects are mediated by the formation of stress fibers and the consequent clustering of α5β1...

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Detalhes bibliográficos
Main Authors: Roovers, Kristin, Assoian, Richard K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156148/
https://ncbi.nlm.nih.gov/pubmed/12773570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.12.4283-4294.2003
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