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Deacetylase Activity Is Required for Recruitment of the Basal Transcription Machinery and Transactivation by STAT5

The signal transducer and activator of transcription STAT5 plays a major role in the cellular response to cytokines, but the mechanism by which it activates transcription remains poorly understood. We show here that deacetylase inhibitors (trichostatin A, suberoylanilide hydroxamic acid, and sodium...

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Détails bibliographiques
Auteurs principaux: Rascle, Anne, Johnston, James A., Amati, Bruno
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC156147/
https://ncbi.nlm.nih.gov/pubmed/12773560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.12.4162-4173.2003
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