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A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis
Regulated expression of Ikaros is critical for normal hemopoiesis and lymphocyte development. To elucidate the mechanisms underlying transcription of Ikaros, tissue-specific DNase I-hypersensitive sites (DHS) were mapped throughout the Ikaros locus, and several promoters were identified. The activit...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156063/ https://ncbi.nlm.nih.gov/pubmed/12727887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg186 |
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