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S. pombe CLASP needs dynein, not EB1 or CLIP170, to induce microtubule instability and slows polymerization rates at cell tips in a dynein-dependent manner
The Schizosaccharomyces pombe CLIP170-associated protein (CLASP) Peg1 was identified in a screen for mutants with spindle formation defects and a screen for molecules that antagonized EB1 function. The conditional peg1.1 mutant enabled us to identify key features of Peg1 function. First, Peg1 was re...
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Hoofdauteurs: | , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
2006
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1560416/ https://ncbi.nlm.nih.gov/pubmed/16951255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.381306 |
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