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S. pombe CLASP needs dynein, not EB1 or CLIP170, to induce microtubule instability and slows polymerization rates at cell tips in a dynein-dependent manner

The Schizosaccharomyces pombe CLIP170-associated protein (CLASP) Peg1 was identified in a screen for mutants with spindle formation defects and a screen for molecules that antagonized EB1 function. The conditional peg1.1 mutant enabled us to identify key features of Peg1 function. First, Peg1 was re...

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Bibliografische gegevens
Hoofdauteurs: Grallert, Agnes, Beuter, Christoph, Craven, Rachel A., Bagley, Steve, Wilks, Deepti, Fleig, Ursula, Hagan, Iain M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560416/
https://ncbi.nlm.nih.gov/pubmed/16951255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.381306
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