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Lysosome membrane lipid microdomains: novel regulators of chaperone-mediated autophagy
Chaperone-mediated autophagy (CMA) is a selective mechanism for the degradation of soluble cytosolic proteins in lysosomes. The limiting step of this type of autophagy is the binding of substrates to the lysosome-associated membrane protein type 2A (LAMP-2A). In this work, we identify a dynamic subc...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1560360/ https://ncbi.nlm.nih.gov/pubmed/16917501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601283 |
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