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Aberrant Metabolites in Mouse Models of Congenital Blinding Diseases: Formation and Storage of Retinyl Esters

Regeneration of the visual chromophore, 11-cis-retinal, is a critical step in restoring photoreceptors to their dark-adapted conditions. This regeneration process, called the retinoid cycle, takes place in the photoreceptor outer segments and the retinal pigment epithelium (RPE). Disabling mutations...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Maeda, Akiko, Maeda, Tadao, Imanishi, Yoshikazu, Golczak, Marcin, Moise, Alexander R., Palczewski, Krzysztof
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560103/
https://ncbi.nlm.nih.gov/pubmed/16566595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi052382x
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